P06.11 ENPP3 overexpression in astrocytomas
نویسندگان
چکیده
منابع مشابه
Overexpression of c-erbB2 is a negative prognostic factor in anaplastic astrocytomas
The epidermal growth factor receptor (EGFR) family, consisting of four tyrosine kinase receptors, c-erbB1-4, seems to be influential in gliomagenesis. The aim of this study was to investigate EGFR gene amplification and expression of c-erbB1-4 receptor proteins in human anaplastic astrocytomas. Formalin-fixed and paraffin-embedded sections from 31 cases were investigated by standard immunohisto...
متن کاملMicroglia in gemistocytic astrocytomas.
OBJECTIVE Although gemistocytic astrocytomas are graded as World Health Organization II astrocytomas, they behave more aggressively than other astrocytomas. Their proliferative potential is low, and it remains an intriguing question why these tumors are so biologically "successful." They show a high mutation rate of the P53 gene, cytological abnormalities, and frequent perivascular mononuclear ...
متن کاملDistinct differences in binding capacity to saccharide epitopes in supratentorial pilocytic astrocytomas, astrocytomas, anaplastic astrocytomas, and glioblastomas.
We monitored the expression of glycan-binding sites on a panel of 10 biotinylated neoglycoconjugates by means of quantitative computer-assisted microscopy to further study the molecular mechanisms in the extensive infiltration of the surrounding brain parenchyma by most astrocytic tumors. Three distinct histological compartments were analyzed for each of the 108 astrocytic tumors (15 pilocytic ...
متن کاملLow Grade Astrocytomas
Astrocytomas are tumors that are believed to arise from precursors of astrocytes – supportive cells of the brain named for their star-like shape. Astrocytomas are the most common of the primary brain tumors. The pathologist, using a microscope, grades these tumors on a scale of I to IV based on how quickly the cells are reproducing, as well as their potential to invade nearby tissue. Grade IV a...
متن کاملAnaplastic Astrocytomas and Oligodendrogliomas
The recommendations contained in this guideline are a consensus of the Alberta Provincial CNS Tumour Team synthesis of currently accepted approaches to management, derived from a review of relevant scientific literature. Clinicians applying these guidelines should, in consultation with the patient, use independent medical judgment in the context of individual clinical circumstances to direct care.
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Neuro-Oncology
سال: 2017
ISSN: 1522-8517,1523-5866
DOI: 10.1093/neuonc/nox036.185